Glaucoma is the main reason for using medical cannabis and that is why the federal government granted permission for marijuana use. Research dates back to the early 1970’s shows that both cannabis and THC reduces intraocular pressure, a key contribution to glaucoma. The first such reports generated considerable interests because at the time conventional medication for glaucoma a variety of side effects. Conventional therapies for intraocular pressure outperform cannabinoids. The next generation dim drugs is expected to directly treat the disease or even reverse it.
More than 60 million people worldwide are affected by glaucoma, a second leading cause of blindness after cataract. Primary open-angle glaucoma (POAG) is a slowly progressive disorder that distorts the cells in the eye’s retina and breaks down the optic nerve.
Researchers have not yet learned what triggered POAG, but have identified three factors that place people at risk for developing the disease: age, race, and elevated intraocular pressure. 1% of people if age 60 have POAG, more than 9% of people over 80 develop the disease. For African Americans, the numbers are a bit higher to 10 percent and is 25 percent amongst Caribbean people.
The third risk factor, elevated intraocular pressure results from blockage on the flow of fluid that helps the eye keep its shape. Normally This fluid is called aqueous humor circulates between the front of the lens and behind the cornea. Because elevated intro-ocular pressure is the only big risk factor for glaucoma that can be controlled, most treatments have been designed to reduce it.
Drugs can alter intraocular pressure by acting on different circulation routes of the aqueous humor. One important outflow to route is the trabecular meshwork, a lattice work of connective tissues and cells.
There are surgical options for controlling intraocular pressure. The trabecular meshwork can be cut with a laser, allowing the fluid to move out of it more easily. A surgeon can remove a piece of the eye wall and allow fluid to drain out under the conjuctiva. Doctors can also insert tiny drainage tubes inside the eye yo allow fluid to drainage to the outer layers of the eye.
Many clinical studies show that cannabinoids reduce intraocular pressure (IOP) as well S most glaucoma medications. Smoked or eaten marijuana, THE and synthetic cannabinoids in pill for, and intravenous injunctions of many natural cannabinoids have been shown to reduce OPP drastically in glaucoma patients and healthy adults.
While cannabis is affective in reducing OPP, cannabis-based-treatments has numerous drawbacks. Cannabis refuses blood pressure and produces psychological effect that some people find intolerable. The short term duration of effect means that marijuana-based medications be taken up to eight times a day. Other medications reduce IOP equally well and need only be taken once or twice a day.