Marijuana & Epilepsy

Case of study

Perhaps the most well-known case study about the application of cannabis in epilepsy is the one in the 9-year-old Colorado resident “Charlotte Figi”. After not responding to conventional medical treatments, his disease experienced a drastic improvement with the administration of cannabis oil, which contained both CBD and THC. Charlotte went from suffering a horrible 50 seizures a day, to only 2 or 3 a month. It is a spectacular advance in the field of cannabis for medical use, something that proves that CBD and THC are effective medicines and their research should be the absolute priority. His case was published in the journal “Epilepsies” where the authors referred to the oil with THC and CBD: “This extract, applied progressively for weeks, in combination with its usual antiepileptic treatment, reduced the frequency of epileptic attacks in Charlotte from almost 50 daily seizure attacks up to 2-3 nocturnal convulsions a month. This effect has continued for the past 20 months, and Charlotte has successfully left behind her other epileptic drugs. We have briefly reviewed the documented records, preclinical and clinical data, and the controversies surrounding the use of therapeutic marijuana for the treatment of epilepsy, getting to the conclusion that the effect of isolating and treating cannabis compounds at the pharmaceutical level could be lower than the therapies with extracts from the whole plant.


Several studies have been carried out to research the effects that cannabis has on epileptic seizures. Researchers from the departments of Neurology, Pharmacology and Toxicology at the University of Virginia have studied the effects of cannabis on epilepsy for some time now and demonstrated that cannabinoids are effective for the treatment of these severe episodes, by interacting with the CB1 receptor, a component of the endocannabinoid system. These researchers studied the effects of cannabinoids in animals suffering from attacks, stating that, “although marijuana is illegal in the United States, and many other countries. There are many cases of patients nationally and internationally, who defend that marijuana has had therapeutic effects for them. in the relief of a variety of diseases, including epilepsy.

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